Scientists are bringing precision medicine to rheumatoid arthritis for the first time by using genetic profiling of joint tissue to see which drugs will work for which patients, reports a new multi-site study. In the near future, patients won’t have to waste time and be disappointed with months of ineffective therapy, scientists said. Currently $2.5 billion a year is wasted on therapy that doesn’t work.
A group of researchers has found that one of the hundreds of components in scorpion venom can reduce the severity of rheumatoid arthritis in animal models, without inducing side effects associated with similar treatments.
Respiratory disease patients with arthritis could struggle to manage their conditions because their inhalers are too fiddly for them to use, new research has found.
Inflammation needs energy: An important source for this energy is oxygen, which is indispensable for the cells of the immune system to work properly. On the one hand, oxygen is an essential element required for cells to survive; on the other hand, it also adds fuel to the fire of inflammation. Researchers have discovered that the body skilfully uses this process to extinguish inflammation.
An off-label drug prescribed to treat osteoarthritis of the hand when conventional medication has failed is ineffective, according to new research. The study shows there was no benefit in taking hydroxychloroquine to control debilitating pain when compared to a placebo (dummy substance).
Scientists have discovered a molecule that enhances cartilage regeneration and decreases inflammation.
Scientists believe they identified a mechanism that activates T cells, a key component of the immune system, which could explain the elusive link between a tick bite and persistent Lyme arthritis.
Platelets play a much bigger role in our immune system than previously thought, according to researchers. In addition to their role in coagulation and healing, platelets also act as the immune system’s first responders when a virus, bacterium, or allergen enters the bloodstream. This discovery opens the door to new ways to treat patients with septic shock caused by viral or bacterial infection and people with auto-immune diseases like rheumatoid arthritis and lupus.
A strain of bacteria commonly found in milk and beef may be a trigger for developing rheumatoid arthritis in people who are genetically at risk, according to a new study.
A recent study suggests that women with rheumatoid arthritis suffer a greater decline in physical function following menopause. After studying 8,189 women with rheumatoid arthritis, researchers found that pre-menopausal women experienced a slower physical decline than those that were post-menopausal.