An international team of researchers has unraveled a crucial aspect of the molecular basis of autoimmune and inflammatory diseases such as psoriasis, rheumatoid arthritis and Crohn’s disease. Focusing on the immunomodulatory cytokine IL-23 they discovered that its pro-inflammatory activity, which underlies a wide range of inflammatory diseases, critically depends on structural activation of the cytokine by its receptor, IL-23R.
The frequency of chronic joint pain after infection with chikungunya in a large Latin-American cohort was 25 percent at a median of 20-months post-infection.
Treatment for the most deadly form of skin cancer could be more effective if combined with a well-known drug for rheumatoid arthritis, new research has shown.
New research reveals that children born to women with rheumatoid arthritis face an increased susceptibility for certain chronic diseases.
Results suggest that the findings from previous studies regarding lower weight being associated with higher mortality may not be directly related to RA and instead reflect a more generalized phenomenon.
New research provides insights on the potential effects of weight on the health of individuals with rheumatoid arthritis (RA).
New research indicates that the prevalence of arthritis in the United States has been substantially underestimated, especially among adults <65 years old.
Maintaining sufficient vitamin D levels may help to prevent the onset of inflammatory diseases like rheumatoid arthritis, research has discovered.
Researchers have discovered a potent, drug-like compound that could someday revolutionize treatment of rheumatoid arthritis and other autoimmune diseases.
A peptide only found in Old World monkeys has the potential to stop rheumatoid arthritis progression better than established treatments, new research indicates.