Researchers are pursuing a new approach to treating arthritis. This is based on a polysaccharide, a long-chain sugar molecule, originating from brown algae. When chemically modified, this ‘alginate’ reduces oxidative stress, has an anti-inflammatory effect in cell culture tests and suppresses the immune reaction against cartilage cells, thereby combating the causes of arthritis. The research is, however, still in its infancy.
Taking the contraceptive pill, particularly for seven or more consecutive years, is linked to a lowered risk of developing rheumatoid arthritis.
A new drug-like molecule appears to intercede in an inflammatory response that is at the center of a variety of diseases, including some cancers, rheumatoid arthritis and Crohn’s disease.
Mutations in the gene encoding the enzyme protein tyrosine phosphatase N2 (PTPN2) have been associated with the development of autoimmune disease including Type 1 diabetes, Crohn’s Disease and rheumatoid arthritis.
Rheumatoid arthritis is the most common autoimmune disease of the joints. It causes a chronic inflammatory response, with the body’s own immune cells attacking the joint, including the cartilage and bone. This process does not cease spontaneously. Medical researchers have now managed to identify an immune system cell type that can be used in a targeted attempt to control the inflammatory response in arthritis patients.
New research indicates that certain occupations may put workers at an elevated risk of developing rheumatoid arthritis. The findings suggest that work-related factors, such as noxious airborne agents, may contribute to the pathogenesis of rheumatoid arthritis. Environmental factors are thought to play a role in the development of rheumatoid arthritis by triggering autoimmune reactions in susceptible individuals.
New research indicates that weather conditions in 45 US cities are indeed associated with Google searches about joint pain. But it might not be the association you’d expect. The findings suggest that people’s activity level — increasing as temperatures rise, to a point — is likelier than the weather itself to spur online searches about knee and hip pain, the investigators say.
A protein which protects the fetus during pregnancy, HLA-G1, shows high potential for treating atopic dermatitis and other related diseases.
A drug used for arthritis could be used to treat blood cancer, scientists have found. Polycythemia vera, a type of blood cancer, affects 3,000 people a year. This breakthrough offers an affordable and effective treatment, say the investigators.
A noninvasive treatment for knee arthritis has been developed that uses cooled radio energy to target and interrupt pain signals. Known as “Coolief,” the procedure can provide several months of relief from chronic arthritis pain for patients for whom surgery is not an option.