An unexpected discovery in two disease-linked proteins could shed light on human immune system disorders, including a rare and often fatal childhood disease called hemophagocytic lymphohistiocytosis (HLH).
Researchers have found that carbohydrate composition of diets increased the risk of osteoarthritis in laboratory mice — even when the animals didn’t differ in weight.
Immunologists have demonstrated that ILC2, a group of rare lymphoid cells, play a key role in the development of inflammatory arthritis. ILCs have several functional similarities to T-cells and are important agents of our congenital immune system. The researchers’ findings could form the basis for new approaches for treating rheumatoid arthritis.
The finding could lead to targeted therapies for chronic conditions.
Researchers have identified a new gene that plays a critical role in regulating the body’s immune response to infection and disease.
Overweight and obese individuals with knee osteoarthritis can reduce pain and significantly improve function and mobility with weight loss. New research reveals that a 20% or more weight loss has the added benefit of continued improvement in physical health-related quality of life along with an additional 25% reduction in pain and improvement in function.
An algorithm to monitor the joints of patients with arthritis, which could change the way that the severity of the condition is assessed, has been developed by a team of engineers, physicians and radiologists.
The results of the study demonstrate increased levels of gum disease, and disease-causing bacteria, in individuals at risk of rheumatoid arthritis (RA).
Drugs used to treat rheumatoid arthritis may impact mental health by improving pain and stiffness and by targeting inflammatory processes common to arthritis and depression; however, a recent review demonstrates that relying on rheumatoid arthritis therapies alone may not meaningfully improve patients’ mental health.
A new study has revealed that pregnant women with rheumatoid arthritis (RA) may be able to use certain RA drugs without possible increased health risks to their unborn babies.