Taking the contraceptive pill, particularly for seven or more consecutive years, is linked to a lowered risk of developing rheumatoid arthritis.
Mutations in the gene encoding the enzyme protein tyrosine phosphatase N2 (PTPN2) have been associated with the development of autoimmune disease including Type 1 diabetes, Crohn’s Disease and rheumatoid arthritis.
Rheumatoid arthritis is the most common autoimmune disease of the joints. It causes a chronic inflammatory response, with the body’s own immune cells attacking the joint, including the cartilage and bone. This process does not cease spontaneously. Medical researchers have now managed to identify an immune system cell type that can be used in a targeted attempt to control the inflammatory response in arthritis patients.
New research indicates that certain occupations may put workers at an elevated risk of developing rheumatoid arthritis. The findings suggest that work-related factors, such as noxious airborne agents, may contribute to the pathogenesis of rheumatoid arthritis. Environmental factors are thought to play a role in the development of rheumatoid arthritis by triggering autoimmune reactions in susceptible individuals.
A protein which protects the fetus during pregnancy, HLA-G1, shows high potential for treating atopic dermatitis and other related diseases.
A drug used for arthritis could be used to treat blood cancer, scientists have found. Polycythemia vera, a type of blood cancer, affects 3,000 people a year. This breakthrough offers an affordable and effective treatment, say the investigators.
A noninvasive treatment for knee arthritis has been developed that uses cooled radio energy to target and interrupt pain signals. Known as “Coolief,” the procedure can provide several months of relief from chronic arthritis pain for patients for whom surgery is not an option.
Young patients who suffer patellar dislocations are at a higher risk of recurring dislocations, especially long-term after their initial injury, according to research.
A pattern of genes has been identified that is characteristic of osteoarthritis and may be a step towards better treatments for this condition.
A previously unknown group of regulatory T cells have been found to be linked to juvenile arthritis and DNA features that affect patients’ response to treatment. These findings pave the way for improved juvenile arthritis diagnosis and prediction of treatment outcomes, and are also relevant for adult rheumatoid arthritis.