Autoimmune diseases significantly increase cardiovascular risk as well as overall mortality, new research confirms. This is particularly pronounced in people suffering rheumatoid arthritis or systemic lupus erythematosus. In addition, it has been seen that inflammatory bowel diseases, such as Crohn’s or ulcerative colitis, increase the risk of stroke and death through any cause.
Ibuprofen is associated with increased blood pressure and hypertension compared to celecoxib in patients with osteoarthritis or rheumatoid arthritis and increased risk of cardiovascular disease, according to new research.
New research indicates that the live varicella-zoster vaccine — which is given to protect against shingles — elicits robust immune responses in patients when administered several weeks prior to the start of treatment with the arthritis drug tofacitinib.
Researchers are pursuing a new approach to treating arthritis. This is based on a polysaccharide, a long-chain sugar molecule, originating from brown algae. When chemically modified, this ‘alginate’ reduces oxidative stress, has an anti-inflammatory effect in cell culture tests and suppresses the immune reaction against cartilage cells, thereby combating the causes of arthritis. The research is, however, still in its infancy.
Taking the contraceptive pill, particularly for seven or more consecutive years, is linked to a lowered risk of developing rheumatoid arthritis.
A new drug-like molecule appears to intercede in an inflammatory response that is at the center of a variety of diseases, including some cancers, rheumatoid arthritis and Crohn’s disease.
Mutations in the gene encoding the enzyme protein tyrosine phosphatase N2 (PTPN2) have been associated with the development of autoimmune disease including Type 1 diabetes, Crohn’s Disease and rheumatoid arthritis.
Rheumatoid arthritis is the most common autoimmune disease of the joints. It causes a chronic inflammatory response, with the body’s own immune cells attacking the joint, including the cartilage and bone. This process does not cease spontaneously. Medical researchers have now managed to identify an immune system cell type that can be used in a targeted attempt to control the inflammatory response in arthritis patients.
New research indicates that certain occupations may put workers at an elevated risk of developing rheumatoid arthritis. The findings suggest that work-related factors, such as noxious airborne agents, may contribute to the pathogenesis of rheumatoid arthritis. Environmental factors are thought to play a role in the development of rheumatoid arthritis by triggering autoimmune reactions in susceptible individuals.
New research indicates that weather conditions in 45 US cities are indeed associated with Google searches about joint pain. But it might not be the association you’d expect. The findings suggest that people’s activity level — increasing as temperatures rise, to a point — is likelier than the weather itself to spur online searches about knee and hip pain, the investigators say.